The Centre de Coordination de la Lutte Anti-drogue en Méditerranée, or Coordination Centre for Anti-Drug Enforcement in the Mediterranean area was established in 2008 during the French Presidency of the EU. It is based near Paris, France, and is closely modelled on MAOC-N in Lisbon. The centre aims to intercept drug trafficking from Northern and Western Africa in the Mediterranean.

The Mediterranean Coast Guard Functions Forum (MCGFF) is a non-binding, voluntary, independent and non-political forum bringing together representatives from institutions and agencies with related competencies in coast guard functions in the Mediterranean. The aim is to facilitate multilateral cooperation on a wide range of issues such as maritime safety, security and environmental protection activities as well as creating partnerships to share experience and best practices on common problems.

The Directive 2002/59/EC of the European Parliament and of the Council of 27 June 2002 requires the Member States (MSs) to provide themselves with appropriate equipment and shore-based installations for receiving and utilizing the AIS information transmitted by the vessels. The Member States agreed to implement common regional systems hosted and developed by one of them. EMSA and the Italian Coast Guard subscribed, since 2009, a Service Level Agreement (SLA) by which Italy is responsible for the hosting, maintenance, operation, and monitoring of the Mediterranean AIS Regional Server (MAREΣ) and its connection with SafeSeaNet. Part of SafeSeaNet, MAREΣ (Mediterranean AIS Regional Exchange System) officially started to run on 1st January 2008; currently it allows the AIS information sharing among Mediterranean EU countries (Portugal, Spain, France, Italy, Malta, Slovenia, Greece, Cyprus, Romania, Bulgaria, Croatia) and non-EU which agreed to share AIS data between themselves (e.g., Jordan, Morocco, and Montenegro).

The Barcelona Convention aims to address in a holistic manner all sources of pollution, which may threaten the marine environment of the Mediterranean and its coastal areas. In particular, the Protocol Concerning Cooperation in Preventing Pollution from Ships and, in Cases of Emergency, Combating Pollution of the Mediterranean Sea is the legal framework within which regional cooperation in the fields of prevention of and response to marine pollution from ships is developing. A regional strategy aims to improve the follow-up of pollution events and monitoring/surveillance of illicit discharges. The 22 Contracting Parties are Albania, Algeria, Bosnia and Herzegovina, Croatia, Cyprus, Egypt, France, Greece, Israel, Italy, Lebanon, Libya, Malta, Monaco, Montenegro, Morocco, Slovenia, Spain, Syria, Tunisia, Turkey, and the EU.

The ARCSAR network addresses the Arctic and North-Atlantic (ANA) region, preparing to cope with the Security and safety threats that will result from increased commercial activity in the region including traffic through the Northern passages, cruise traffic, and offshore oil and gas activity. It aims to establish and support a new Arctic and North Atlantic Security and Emergency Preparedness Network for those involved in front-line security and emergency response, directly involving practitioners, existing networks, university stakeholders, research centres, industry, and those involved in governance, and policy-making.