The Centre de Coordination de la Lutte Anti-drogue en Méditerranée, or Coordination Centre for Anti-Drug Enforcement in the Mediterranean area was established in 2008 during the French Presidency of the EU. It is based near Paris, France, and is closely modelled on MAOC-N in Lisbon. The centre aims to intercept drug trafficking from Northern and Western Africa in the Mediterranean.

The Bucharest Convention was signed in Bucharest in April 1992, and was ratified by all six legislative assemblies of the Black Sea countries (i.e. Bulgaria, Georgia, Romania, Russian Federation, Turkey and Ukraine) in 1994. It is the basic framework of agreement and has three specific Protocols, dealing with the control of land-based sources of pollution, the dumping of waste, and joint action in the case of accidents (such as oil spills). The implementation of the Convention is managed by the Commission for the Protection of the Black Sea Against Pollution (also sometimes referred to as the Istanbul Commission), and its Permanent Secretariat is in Istanbul, Turkey.

The Mediterranean Coast Guard Functions Forum (MCGFF) is a non-binding, voluntary, independent and non-political forum bringing together representatives from institutions and agencies with related competencies in coast guard functions in the Mediterranean. The aim is to facilitate multilateral cooperation on a wide range of issues such as maritime safety, security and environmental protection activities as well as creating partnerships to share experience and best practices on common problems.

The Directive 2002/59/EC of the European Parliament and of the Council of 27 June 2002 requires the Member States (MSs) to provide themselves with appropriate equipment and shore-based installations for receiving and utilizing the AIS information transmitted by the vessels. The Member States agreed to implement common regional systems hosted and developed by one of them. EMSA and the Italian Coast Guard subscribed, since 2009, a Service Level Agreement (SLA) by which Italy is responsible for the hosting, maintenance, operation, and monitoring of the Mediterranean AIS Regional Server (MAREΣ) and its connection with SafeSeaNet. Part of SafeSeaNet, MAREΣ (Mediterranean AIS Regional Exchange System) officially started to run on 1st January 2008; currently it allows the AIS information sharing among Mediterranean EU countries (Portugal, Spain, France, Italy, Malta, Slovenia, Greece, Cyprus, Romania, Bulgaria, Croatia) and non-EU which agreed to share AIS data between themselves (e.g., Jordan, Morocco, and Montenegro).

The Bonn Agreement is the mechanism by which ten Governments, together with the European Union, cooperate in dealing with pollution of the North Sea by oil and other harmful substances. The signatories to the Agreement are the Governments of Belgium, Denmark, France, Germany, Ireland, Netherlands, Norway, Sweden, the UK, and the European Union. Spain joined as a Contracting Party in 2019.

The Black Sea Cooperation Forum was established in 2000, between the Coast Guard / Border Authorities of the Black Sea states, namely Turkey, Bulgaria, Romania, Ukraine, Russian Federation and Georgia. The main purpose is to enhance peace, stability and maritime security in the Black Sea area, by increasing regional co-operation, and improving good relationship. Its tasks include enhancing existing interaction among border/coast guard agencies to prevent illegal activities, as well as strengthening the safety and security of navigation in the Black Sea. It conducts counterterrorism and weapon of mass destruction non-proliferation activities. It aims to help improve cooperation in the areas of fishery protection, search and rescue, marine pollution, marine environmental protection, information exchange, personnel exchange programs, joint/shared training.

The Barcelona Convention aims to address in a holistic manner all sources of pollution, which may threaten the marine environment of the Mediterranean and its coastal areas. In particular, the Protocol Concerning Cooperation in Preventing Pollution from Ships and, in Cases of Emergency, Combating Pollution of the Mediterranean Sea is the legal framework within which regional cooperation in the fields of prevention of and response to marine pollution from ships is developing. A regional strategy aims to improve the follow-up of pollution events and monitoring/surveillance of illicit discharges. The 22 Contracting Parties are Albania, Algeria, Bosnia and Herzegovina, Croatia, Cyprus, Egypt, France, Greece, Israel, Italy, Lebanon, Libya, Malta, Monaco, Montenegro, Morocco, Slovenia, Spain, Syria, Tunisia, Turkey, and the EU.

The Baltic Sea Task Force on Organised Crime (BSTF-OC) was created in 1996 in Visby (Sweden) through a decision of the Heads of Governments of the Baltic Sea States. It comprises 11 personal representatives of the Heads of Governments of the Baltic Sea States (Denmark, Estonia, Finland, Germany, Iceland, Latvia, Lithuania, Norway, Poland, Russia and Sweden). Officials from Interpol, Europol, the EU Council and the Secretariat of the Council of the Baltic Sea States have the status of observers at the BSTF meetings.

BALTFISH was initiated in 2009 as a flagship project within the EU Strategy for the Baltic Sea Region, EUSBSR. A Memorandum of Understanding was signed in December 2013 by the ministers in the eight member states in the Baltic Sea Region, and thus changing the status of BALTFISH from a flagship project to a permanent fisheries forum. BALTFISH works on two levels. There is a high-level group (HLG) composed of the Member States fisheries directors and invited officials from the European Commission. There is also the BALTFISH Forum Seminar composed of representatives from Member States, the European Commission and the Baltic Sea Advisory Council as well as representatives from other relevant stakeholders in the Baltic Sea fisheries.

The Baltic Sea Region Border Control Cooperation (BSRBCC) is a flexible regional tool for daily inter-agency interaction in the field of environmental protection. It also aims to combat cross-border crime in the Baltic Sea region, with a particular focus on the maritime environment. Cooperation Partners are Police, Border Guards, Coast Guards and Customs Authorities. The BSRBCC Border Guard Chiefs meet annually and is responsible for the cooperation initiative, and approving the operational strategy. It also has an operational and economic mandate for cooperation. The BSRBCC presidency, which is for one year, is supported by a secretariat, which includes representatives from the last, current and next Presidency, thereby ensuring continuity. The Baltic Border Committee (BBC) prepares and implements the cooperation strategy through joint operations, where national representatives integrate national action and local cooperation into wider cooperation as necessary. Each MS operates a 24/7 National Coordination Centre (NCC), whilst the Presidency maintains an International Coordination Centre (ICC).